Question 1

What is radiopharmaceutical theranostics?

Accepted Answer

Radiopharmaceutical theranostics combines diagnostic imaging and targeted therapy using radioactive compounds. The same or similar molecular targeting agent is labeled with different radioisotopes—one for imaging to identify and locate tumors, and another for delivering therapeutic radiation directly to cancer cells. This approach enables personalized treatment by confirming target expression before therapy.

Question 2

What radionuclides does RPT Labworks work with?

Accepted Answer

We work with a comprehensive range of radionuclides for both imaging and therapy. Imaging isotopes include Cu-64, F-18, Ga-68, I-123, I-124, In-111, Tc-99m, Y-86, and Zr-89. Therapeutic isotopes include Ac-225, Cu-67, I-131, Lu-177, Pb-212, Ra-223, Tb-161, and Y-90. We are radionuclide-agnostic and can adapt to your specific program requirements.

Question 3

What is the typical turnaround time for studies?

Accepted Answer

Most preclinical studies are completed within 2-4 weeks from study start to comprehensive report delivery. Exact timelines depend on study complexity, the number of time points, and specific assay requirements. We work closely with clients to establish realistic timelines and can accommodate urgent projects when needed.

Question 4

Where is RPT Labworks located?

Accepted Answer

Our 6,000 square foot facility is located in Madison, Wisconsin, at the heart of the region's thriving personalized medicine ecosystem. We benefit from proximity to the University of Wisconsin, major isotope suppliers, and a vibrant biotech community. Our address is 918 Deming Way, Suite 101, Madison, WI 53717.

Question 5

What is the difference between in vitro and in vivo studies?

Accepted Answer

In vitro studies are conducted in controlled laboratory environments using cells, tissues, or biological molecules outside a living organism. These include binding assays, internalization studies, and cytotoxicity testing. In vivo studies are performed in living animal models to evaluate biodistribution, efficacy, and safety in a complete biological system with PET/SPECT imaging capabilities.

Question 6

What is dosimetry and why is it important?

Accepted Answer

Dosimetry quantifies the radiation dose absorbed by different tissues and organs following radiopharmaceutical administration. It's essential for predicting therapeutic efficacy, establishing safe dose levels, and optimizing the therapeutic index. We offer image-based, ex vivo, and OLINDA-based dosimetry approaches to support IND applications.

Question 7

Do you offer consulting for early-stage programs?

Accepted Answer

Yes, we provide comprehensive consulting services for programs at any stage. For early-stage programs, we can help with method development strategy, experimental design optimization, and preclinical IND support. Our experts can guide you through regulatory pathway considerations and help de-risk your development program.

Question 8

What quality standards does RPT Labworks follow?

Accepted Answer

We maintain rigorous quality standards with meticulously calibrated equipment and validated protocols. Our team follows Good Laboratory Practice (GLP) principles where applicable, and we provide detailed documentation to support regulatory submissions. All studies include comprehensive quality control testing and thorough data review.

Question 9

How do I start a project with RPT Labworks?

Accepted Answer

Getting started is simple: contact us to schedule a consultation where we'll discuss your program goals, compound characteristics, and study requirements. We'll provide a detailed proposal including scope, timeline, and pricing. Once approved, our team will work with you to finalize the study protocol and coordinate compound shipping.

Question 10

What information do you need to provide a quote?

Accepted Answer

To provide an accurate quote, we typically need: your compound type and characteristics, desired radionuclide(s), study objectives, number of groups and time points, specific assays required, and your target timeline. The more details you can provide, the more precise our proposal will be.

Question 11

Can you work with our existing protocols?

Accepted Answer

Absolutely. We're experienced in adapting to client-specific protocols and requirements. Our team can also help optimize existing methods or develop new approaches tailored to your compound's unique characteristics. We maintain flexibility to ensure our services align with your program needs.

Question 12

What makes RPT Labworks different from other CROs?

Accepted Answer

RPT Labworks offers specialized expertise focused exclusively on radiopharmaceutical theranostics. Our team brings decades of combined experience in nuclear medicine, molecular imaging, and cancer biology. We provide end-to-end services under one roof, eliminating coordination delays between multiple vendors, and deliver results in 2-4 weeks with our integrated workflow approach.

Frequently Asked Questions

Still have questions?